PPP6C Antibody

Size

100ug

Clone Number

Aliases

FLJ92648 antibody; MGC12249 antibody; PP 6 antibody; PP6 antibody; PP6C antibody; PPP 6 antibody; PPP 6C antibody; PPP6 antibody; PPP6_HUMAN antibody; Ppp6c antibody; Protein phosphatase 6 catalytic subunit antibody; Serine/threonine protein phosphatase 6 antibody; Serine/threonine protein phosphatase catalytic subunit antibody; Serine/threonine-protein phosphatase 6 catalytic subunit antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O00743

Immunogen

Recombinant Human Serine/threonine-protein phosphatase 6 catalytic subunit protein (40-211AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Catalytic subunit of protein phosphatase 6 (PP6). PP6 is a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation. N-terminal domain restricts G1 to S phase progression in cancer cells, in part through control of cyclin D1. Downregulates MAP3K7 kinase activation of the IL1 signaling pathway by dephosphorylation of MAP3K7.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

PPP6C

Research Areas

Signal transduction