PPP2R5C Antibody

Size

100ul

Clone Number

Aliases

2A5G_HUMAN antibody; B' alpha regulatory subunit antibody; B56G antibody; KIAA0044 antibody; MGC23064 antibody; PP2A B subunit B' gamma isoform antibody; PP2A B subunit B56 gamma isoform antibody; PP2A B subunit isoform B' gamma antibody; PP2A B subunit isoform B''-gamma antibody; PP2A B subunit isoform B56-gamma antibody; PP2A B subunit isoform PR61-gamma antibody; PP2A B subunit isoform R5-gamma antibody; PP2A B subunit PR61 gamma isoform antibody; PP2A B subunit R5 gamma isoform antibody; Ppp2r5c antibody; PR61G antibody; Protein phosphatase 2 regulatory subunit B (B56) gamma isoform antibody; Protein phosphatase 2 regulatory subunit B' gamma antibody; Protein phosphatase 2; regulatory subunit B'; gamma isoform antibody; Renal carcinoma antigen NY REN 29 antibody; Renal carcinoma antigen NY-REN-29 antibody; Serine/threonine protein phosphatase 2A 56 kDa regulatory subunit gamma isoform antibody; Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q13362

Immunogen

Recombinant Human Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform protein (1-320AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background

The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. The PP2A-PPP2R5C holoenzyme may specifically dephosphorylate and activate TP53 and play a role in DNA damage-induced inhibition of cell proliferation. PP2A-PPP2R5C may also regulate the ERK signaling pathway through ERK dephosphorylation.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

PPP2R5C

Research Areas

Neuroscience; Signal transduction