ABCbiolab
SKU:ABCCS64633
PPP1R13L Antibody
PPP1R13L Antibody
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Size
100ul
Clone Number
Aliases
PPP1R13L antibody; IASPP antibody; NKIP1 antibody; PPP1R13BL antibody; RAI antibody; RelA-associated inhibitor antibody; Inhibitor of ASPP protein antibody; Protein iASPP antibody; NFkB-interacting protein 1 antibody; PPP1R13B-like protein antibody
Immunogen Species
Homo sapiens (Human)
UniProt ID
Q8WUF5
Immunogen
Peptide sequence from Human RelA-associated inhibitor protein (83-102AA)
Raised in
Rabbit
Species Reactivity
Human
Tested Applications
ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200
Background
Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis.
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Conjugate
Non-conjugated
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Stroage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names
PPP1R13L
Research Areas
Epigenetics and Nuclear Signaling; Cancer; Cell biology
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