Ppp1cb Antibody

Size

100ug

Clone Number

Aliases

Ppp1cb antibody; Serine/threonine-protein phosphatase PP1-beta catalytic subunit antibody; PP-1B antibody; EC 3.1.3.16 antibody; EC 3.1.3.53 antibody

Immunogen Species

Mus musculus (Mouse)

UniProt ID

P62141

Immunogen

Recombinant Mouse Serine/threonine-protein phosphatase PP1-beta catalytic subunit protein (2-327AA)

Raised in

Rabbit

Species Reactivity

Mouse, Rat

Tested Applications

ELISA, WB; Recommended dilution: WB:1:500-1:5000

Background

Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

Ppp1cb

Research Areas

Others