PPARA Antibody

Size

100ul

Clone Number

Aliases

hPPAR antibody; MGC2237 antibody; MGC2452 antibody; NR1C1 antibody; Nuclear receptor subfamily 1 group C member 1 antibody; OTTHUMP00000197740 antibody; OTTHUMP00000197741 antibody; Peroxisome proliferative activated receptor alpha antibody; Peroxisome proliferator activated receptor alpha antibody; Peroxisome proliferator-activated receptor alpha antibody; PPAR antibody; PPAR-alpha antibody; ppara antibody; PPARA_HUMAN antibody; PPARalpha antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q07869

Immunogen

Recombinant Human Peroxisome proliferator-activated receptor alpha protein (1-237AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB; Recommended dilution: WB:1:1000-1:5000

Background

Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Antigen Affinity purified & Affinity purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

PPARA

Research Areas

Others