PP2B-A alpha Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

Catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.|cofactor:Binds 1 Fe(3+) ion per subunit.|cofactor:Binds 1 zinc ion per subunit.|Calcium-dependent| calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates HSPB1 and SSH1.|online information:Calcineurin entry|Belongs to the PPP phosphatase family.|Belongs to the PPP phosphatase family. PP-2B subfamily.|subcellular location:Colocalizes with ACTN1 and MYOZ2 at the Z line in heart and skeletal muscle.|subunit:Composed of two components (A and B)| the A component is the catalytic subunit and the B component confers calcium sensitivity. Interacts with TORC2/CRTC2| MYOZ1| MYOZ2 and MYOZ3.|

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human PP2B-Aα

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

57310

synonyms

PP2B-Aα; Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform; EC 3.1.3.16; CAM-PRP catalytic subunit; Calmodulin-dependent calcineurin A subunit alpha isoform