POU2F1 Antibody, Biotin conjugated

Size

100ug

Clone Number

Aliases

FLJ42836 antibody; NF A1 antibody; NF-A1 antibody; Oct 1 antibody; Oct 1B antibody; Oct-1 antibody; OCT1 antibody; Octamer binding protein 1 antibody; Octamer binding transcription factor 1 antibody; Octamer-binding protein 1 antibody; Octamer-binding transcription factor 1 antibody; OTF 1 antibody; OTF-1 antibody; OTF1 antibody; OTTHUMP00000032348 antibody; OTTHUMP00000032350 antibody; OTTHUMP00000032351 antibody; PO21 antibody; PO2F1 antibody; PO2F1_HUMAN antibody; POU class 2 homeobox 1 antibody; POU domain class 2 transcription factor 1 antibody; POU domain; class 2; transcription factor 1 antibody; POU2F1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P14859

Immunogen

Recombinant Human POU domain, class 2, transcription factor 1 protein (442-743AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Transcription factor that binds to the octamer motif (5\'-ATTTGCAT-3\') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR (By similarity). In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Biotin

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

POU2F1

Research Areas

Epigenetics and Nuclear Signaling