POT1 Polyclonal Antibody

Ab type

Primary antibody

Background

POT1 is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, protection of telomeres 1 functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of POT1 is associated with stomach carcinogenesis and its progression.

Reactivity

Human;Monkey

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human POT1. AA range:247-296

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

71442

synonyms

POT1; Protection of telomeres protein 1; hPot1; POT1-like telomere end-binding protein