POLDIP3 Antibody

Size

100ug

Clone Number

Aliases

46 kDa DNA polymerase delta interaction protein antibody; DNA polymerase delta interacting protein 3 antibody; KIAA1649 antibody; P46 antibody; PDIP3_HUMAN antibody; PDIP46 antibody; POLDIP3 antibody; Polymerase (DNA-directed), delta interacting protein 3 antibody; Polymerase delta interacting protein 46 antibody; Polymerase delta-interacting protein 3 antibody; RNA-binding protein P46 antibody; S6K1 Aly/REF-like target antibody; SKAR antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9BY77

Immunogen

Recombinant Human Polymerase delta-interacting protein 3 protein (100-221AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC, IF, IP; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:20-1:200, IP:1:200-1:2000

Background

Is involved in regulation of translation. Is preferentially associated with CBC-bound spliced mRNA-protein complexes during the pioneer round of mRNA translation. Contributes to enhanced translational efficiency of spliced over nonspliced mRNAs. Recruits activated ribosomal protein S6 kinase beta-1 I/RPS6KB1 to newly synthesized mRNA. Involved in nuclear mRNA export; probably mediated by assoociation with the TREX complex.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

POLDIP3

Research Areas

Epigenetics and Nuclear Signaling