POC1B Antibody

Size

100ul

Clone Number

Aliases

4933430F16Rik antibody; FLJ14923 antibody; FLJ41111 antibody; Pix1 antibody; POC1 centriolar protein homolog B (Chlamydomonas) antibody; POC1 centriolar protein homolog B antibody; POC1B antibody; POC1B_HUMAN antibody; TUWD12 antibody; WD repeat containing protein 51B antibody; WD repeat domain 51B antibody; WD repeat-containing protein 51B antibody; WDR51B antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q8TC44

Immunogen

Recombinant Human POC1 centriolar protein homolog B protein (299-478AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background

Plays an important role in centriole assembly and/or stability and ciliogenesis (PubMed:20008567). Involved in early steps of centriole duplication, as well as in the later steps of centriole length control (PubMed:19109428). Acts in concert with POC1A to ensure centriole integrity and proper mitotic spindle formation. Required for primary cilia formation, ciliary length and also cell proliferation (PubMed:23015594). Required for retinal integrity (PubMed:25044745).

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

POC1B

Research Areas

Cell biology