PNK1(Phospho-Ser114/Thr118) Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage| the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly| seizures| and developmental delay.

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized phosho peptide around human PNK1 (Ser114 and Thr118)

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

PNK1 ;Ser114/Thr118; Bifunctional polynucleotide phosphatase/kinase; DNA 5'-kinase/3'-phosphatase; Polynucleotide kinase-3'-phosphatase [Includes: Polynucleotide 3'-phosphatase; EC 3.1.3.32; 2';3'-polynucleotidase; Polynucleotide 5'-hydroxyl-kinase; EC 2.7.1.78;