PMS1 Polyclonal Antibody

Ab type

Primary antibody

Background

PMS1 encodes a protein belonging to the DNA mismatch repair mutL/hexB family. PMS1 homolog 1, mismatch repair system component is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in PMS1 cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human PMS1. AA range:441-490

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

105830

synonyms

PMS1; PMSL1; PMS1 protein homolog 1; DNA mismatch repair protein PMS1