PLXND1 Antibody

Size

100ug

Clone Number

Aliases

KIAA0620 antibody; MGC75353 antibody; PLEX D1 antibody; PLEXD 1 antibody; PLEXD1 antibody; Plexin-D1 antibody; PlexinD1 antibody; PLXD1_HUMAN antibody; PLXN D1 antibody; PLXND 1 antibody; PLXND1 antibody; PLXND1 protein antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9Y4D7

Immunogen

Recombinant Human Plexin-D1 protein (1-222AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the medulla. Regulates endothelial cell migration. Plays an important role in ensuring the specificity of synapse formation. Required for normal development of the heart and vasculature (By similarity). Mediates anti-angiogenic signaling in response to SEMA3E.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

PLXND1

Research Areas

Cardiovascular