PLXNA2 Antibody

Size

100ul

Clone Number

Aliases

Plexin-A2 antibody; PlexinA2 antibody; PLXA2 antibody; PLXA2_HUMAN antibody; PLXNA2 antibody; Semaphorin receptor OCT antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O75051

Immunogen

Recombinant Human Plexin-A2 protein (300-560AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Coreceptor for SEMA3A and SEMA6A. Necessary for signaling by SEMA6A and class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

PLXNA2

Research Areas

Neuroscience