PLG Antibody

Size

100ul

Clone Number

Aliases

Plasmin antibody; Plasmin heavy chain A antibody; Plasmin light chain B antibody; Plasminogen antibody; PLG antibody; PLMN_HUMAN antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P00747

Immunogen

Recombinant Human Plasminogen protein (103-343AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:1000-1:2000

Background

Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

PLG

Research Areas

Cancer; Cardiovascular; Cell biology