PLCD3 Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a member of the phospholipase C family| which catalyze the hydrolysis of phosphatidylinositol 4|5-bisphosphate to generate the second messengers diacylglycerol and inositol 1|4|5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine| sphingosine| and several phospholipids.

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human PLCD3

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

86790

synonyms

PLCD3