PLCD1 Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a member of the phospholipase C family. Phospholipase C isozymes play critical roles in intracellular signal transduction by catalyzing the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers diacylglycerol (DAG) and inositol triphosphate (IP3). The encoded protein functions as a tumor suppressor in several types of cancer, and mutations in this gene are a cause of hereditary leukonychia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human protein . at AA range: 90-170

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 ;EC 3.1.4.11;Phosphoinositide phospholipase C-delta-1;Phospholipase C-III;PLC-III;Phospholipase C-delta-1;PLC-delta-1