Plakophilin 2 Polyclonal Antibody

Ab type

Primary antibody

Background

PKP2 encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. PKP2 product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13.

Reactivity

Human;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human PKP2. AA range:632-681

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

97399

synonyms

PKP2; Plakophilin-2