PKD2 Polyclonal Antibody

Ab type

Primary antibody

Background

PKD2 (polycystin 2, transient receptor potential cation channel) encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in PKD2 are associated with autosomal dominant polycystic kidney disease type 2.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human PKD2. AA range:778-827

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

96722

synonyms

PKD2; Polycystin-2; Autosomal dominant polycystic kidney disease type II protein; Polycystic kidney disease 2 protein; Polycystwin; R48321