PKD1L1 Antibody

Size

100ug

Clone Number

Aliases

PKD1L1 antibody; UNQ5785/PRO19563 antibody; Polycystic kidney disease protein 1-like 1 antibody; PC1-like 1 protein antibody; Polycystin-1L1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q8TDX9

Immunogen

Recombinant Human Polycystic kidney disease protein 1-like 1 protein (921-1164AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Component of a ciliary calcium channel that controls calcium concentration within primary cilia without affecting cytoplasmic calcium concentration. Forms a heterodimer with PKD2L1 in primary cilia and forms a calcium-permeant ciliary channel that regulates sonic hedgehog/SHH signaling and GLI2 transcription. Does not constitute the pore-forming subunit. Also involved in left/right axis specification downstream of nodal flow: forms a complex with PKD2 in cilia to facilitate flow detection in left/right patterning.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

PKD1L1

Research Areas

Others