PILRA Antibody

Size

100ug

Clone Number

Aliases

Cell surface receptor FDF03 antibody; FDF03 antibody; Inhibitory receptor PILR-alpha antibody; paired immunoglobulin-like receptor alpha antibody; Paired immunoglobulin-like type 2 receptor alpha antibody; PILRA antibody; PILRA_HUMAN antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9UKJ1

Immunogen

Recombinant Human Paired immunoglobulin-like type 2 receptor alpha protein (22-226AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. PILRA is thought to act as a cellular signaling inhibitory receptor by recruiting cytoplasmic phosphatases like PTPN6/SHP-1 and PTPN11/SHP-2 via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules. Receptor for PIANP.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

PILRA

Research Areas

Others