ABCbiolab
SKU:ABCCS58391
PIK3AP1 Antibody, HRP conjugated
PIK3AP1 Antibody, HRP conjugated
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Size
100ug
Clone Number
Aliases
PIK3AP1 antibody; BCAPPhosphoinositide 3-kinase adapter protein 1 antibody; B-cell adapter for phosphoinositide 3-kinase antibody; B-cell phosphoinositide 3-kinase adapter protein 1 antibody
Immunogen Species
Homo sapiens (Human)
UniProt ID
Q6ZUJ8
Immunogen
Recombinant Human Phosphoinositide 3-kinase adapter protein 1 protein (293-404AA)
Raised in
Rabbit
Species Reactivity
Human
Tested Applications
ELISA
Background
Signaling adapter that contributes to B-cell development by linking B-cell receptor (BCR) signaling to the phosphoinositide 3-kinase (PI3K)-Akt signaling pathway. Has a complementary role to the BCR coreceptor CD19, coupling BCR and PI3K activation by providing a docking site for the PI3K subunit PIK3R1. Alternatively, links Toll-like receptor (TLR) signaling to PI3K activation, a process preventing excessive inflammatory cytokine production. Also involved in the activation of PI3K in natural killer cells. May be involved in the survival of mature B-cells via activation of REL.
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Conjugate
HRP
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Stroage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names
PIK3AP1
Research Areas
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