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ABCbiolab

SKU:ABCCS58391

PIK3AP1 Antibody, HRP conjugated

PIK3AP1 Antibody, HRP conjugated

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Size

100ug

Clone Number

Aliases

PIK3AP1 antibody; BCAPPhosphoinositide 3-kinase adapter protein 1 antibody; B-cell adapter for phosphoinositide 3-kinase antibody; B-cell phosphoinositide 3-kinase adapter protein 1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q6ZUJ8

Immunogen

Recombinant Human Phosphoinositide 3-kinase adapter protein 1 protein (293-404AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Signaling adapter that contributes to B-cell development by linking B-cell receptor (BCR) signaling to the phosphoinositide 3-kinase (PI3K)-Akt signaling pathway. Has a complementary role to the BCR coreceptor CD19, coupling BCR and PI3K activation by providing a docking site for the PI3K subunit PIK3R1. Alternatively, links Toll-like receptor (TLR) signaling to PI3K activation, a process preventing excessive inflammatory cytokine production. Also involved in the activation of PI3K in natural killer cells. May be involved in the survival of mature B-cells via activation of REL.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

HRP

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

PIK3AP1

Research Areas

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