PI3R6 Polyclonal Antibody

Ab type

Primary antibody

Background

Phosphoinositide 3-kinase gamma is a lipid kinase that produces the lipid second messenger phosphatidylinositol 3,4,5-trisphosphate. The kinase is composed of a catalytic subunit and one of several regulatory subunits, and is chiefly activated by G protein-coupled receptors. This gene encodes a regulatory subunit, and is distantly related to the phosphoinositide-3-kinase, regulatory subunit 5 gene which is located adjacent to this gene on chromosome 7. The orthologous protein in the mouse binds to both the catalytic subunit and to G(beta/gamma), and mediates activation of the kinase subunit downstream of G protein-coupled receptors. Alternative splicing results in multiple transcript variants.

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human protein . at AA range: 280-360

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

Phosphoinositide 3-kinase regulatory subunit 6 ;Phosphoinositide 3-kinase gamma adapter protein of 87 kDa;p84 PI3K adapter protein;p84 PIKAP;p87 PI3K adapter protein;p87PIKAP