PI 3-kinase p85 Alpha Polyclonal Antibody

Ab type

Primary antibody

Background

Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. PIK3R1 encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in PIK3R1 has been associated with insulin resistance. Alternative splicing of PIK3R1 results in four transcript variants encoding different isoforms.

Reactivity

Rat;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Recombinant Protein of PI 3-kinase p85α

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

83598

synonyms

PIK3R1; GRB1; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol