ABCbiolab
SKU:ABCB14279
PI 3-Kinase p85 alpha(Phospho Tyr607) Polyclonal Antibody
PI 3-Kinase p85 alpha(Phospho Tyr607) Polyclonal Antibody
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Ab type
Primary antibody
Background
Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms.
Reactivity
Human, Mouse, Rat, Chicken
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Immunogen
The antiserum was produced against synthesized peptide derived from human PI3-kinase p85-alpha around the phosphorylation site of Tyr607. AA range:573-622
Storage Stability
-20°C for 1 year
Concentration
1 mg/ml
MolecularWeight_Da
83598
synonyms
Phosphatidylinositol 3-kinase regulatory subunit alpha; PIK3R1; GRB1; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alph
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