Phospho-CaMKII Alpha/Beta/Delta (T305) Polyclonal Antibody

Ab type

Primary antibody

Background

Calcium/calmodulin dependent protein kinase II beta belongs to the serine/threonine protein kinase family and to the Ca (2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of CAMK2B is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Alternative splicing results in multiple transcript variants.

Reactivity

Human;mouse;rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human CaMK2 alpha/beta/delta around the phosphorylation site of Thr305. AA range:271-320

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

54030

synonyms

CAMK2A; CAMKA; KIAA0968; Calcium/calmodulin-dependent protein kinase type II subunit alpha; CaM kinase II subunit alpha; CaMK-II subunit alpha; CAMK2B; CAM2; CAMK2; CAMKB; Calcium/calmodulin-dependent