Phospho-C/EBP  Alpha (T230) Polyclonal Antibody

Ab type

Primary antibody

Background

CEBPA encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The CCAAT/enhancer binding protein alpha functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons.

Reactivity

Human;mouse;rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized phospho-peptide around the phosphorylation site of human C/EBP α (phospho Thr230)

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

37575

synonyms

CEBPA; CCAAT/enhancer-binding protein alpha; C/EBP alpha