Phospho-Blk (Y501) Polyclonal Antibody

Ab type

Primary antibody

Background

BLK (BLK proto-oncogene, Src family tyrosine kinase) encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors.

Reactivity

Human;mouse;rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human BLK around the phosphorylation site of Tyr501. AA range:456-505

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

57706

synonyms

BLK; Tyrosine-protein kinase Blk; B lymphocyte kinase; p55-Blk