Phospho-Bcl-2 (T74) Polyclonal Antibody

Ab type

Primary antibody

Background

BCL2 (BCL2, apoptosis regulator) encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized phospho-peptide around the phosphorylation site of human Bcl-2 (phospho Thr74)

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

26266

synonyms

BCL2; Apoptosis regulator Bcl-2