Phospho-B-Myb (S577) Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by MYBL2, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene.

Reactivity

Human;mouse;rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human B-Myb around the phosphorylation site of Ser577/581. AA range:551-600

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

78764

synonyms

MYBL2; BMYB; Myb-related protein B; B-Myb; Myb-like protein 2