PHC1 Antibody

Size

100ug

Clone Number

Aliases

Early development regulatory protein 1 antibody; hPH1 antibody; mPH1 antibody; PH1 antibody; Phc1 antibody; PHC1_HUMAN antibody; Polyhomeotic-like protein 1 antibody; Rae28 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P78364

Immunogen

Recombinant Human Polyhomeotic-like protein 1 protein (142-225AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A \'Lys-119\', rendering chromatin heritably changed in its expressibility. Required for proper control of cellular levels of GMNN expression.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

PHC1

Research Areas

Epigenetics and Nuclear Signaling; Stem cells