PFK-C Polyclonal Antibody

Ab type

Primary antibody

Background

The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP: D-fructose-6-phosphate-1-phosphotransferase, EC 2. . 1). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM; MIM 610681) and liver (PFKL; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2.

Reactivity

Human;Mouse;Rat;Monkey

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human K6PP. AA range:341-390

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

85596

synonyms

PFKP; PFKF; 6-phosphofructokinase type C; 6-phosphofructokinase; platelet type; Phosphofructo-1-kinase isozyme C; PFK-C; Phosphofructokinase 1; Phosphohexokinase