PELI3 Antibody

Size

100ul

Clone Number

Aliases

E3 ubiquitin protein ligase pellino homolog 3 antibody; MGC35521 antibody; PEL 13 antibody; Peli3 antibody; PELI3_HUMAN antibody; Pellino 3 antibody; Pellino 3 alpha antibody; Pellino E3 ubiquitin protein ligase family member 3 antibody; Pellino homolog 3 (Drosophila) antibody; Pellino-3 antibody; Protein pellino homolog 3 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q8N2H9

Immunogen

Recombinant Human E3 ubiquitin-protein ligase pellino homolog 3 protein (1-280AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates \\\'Lys-63\\\'-linked polyubiquitination of IRAK1. Can activate AP1/JUN and ELK1. Not required for NF-kappa-B activation.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

PELI3

Research Areas

Immunology; Signal transduction