PELI1 Antibody

Size

100ul

Clone Number

Aliases

E3 ubiquitin-protein ligase pellino homolog 1 antibody; PELI1 antibody; PELI1_HUMAN antibody; Pellino E3 ubiquitin protein ligase 1 antibody; Pellino homolog 1 antibody; Pellino protein antibody; Pellino-1 antibody; Pellino-related intracellular-signaling molecule antibody; Pellino1 antibody; PRISM antibody; Protein pellino homolog 1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q96FA3

Immunogen

Recombinant Human E3 ubiquitin-protein ligase pellino homolog 1 protein (1-250AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200

Background

E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates \\\'Lys-63\\\'-linked polyubiquitination of IRAK1 allowing subsequent NF-kappa-B activation.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

PELI1

Research Areas

Signal transduction