PEG10 Monoclonal Antibody

Size

Clone Number

Aliases

EDR, HB-1, Mar2, MEF3L, Mart2, RGAG3

Immunogen Species

Human

UniProt ID

Q86TG7

Immunogen

Purified recombinant human PEG10 protein fragments expressed in E.coli.

Raised in

Mouse

Species Reactivity

Human,Mouse,Rabbit,Pig

Tested Applications

ELISA,WB,IP;Recommended dilution:WB:1:500-1:5000,IP:1:200-1:2000

Background

This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation.

Clonality

Monoclonal

Isotype

IgG1

Purification Method

Affinity purified

Conjugate

Non-conjugated

Buffer

Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol

Form

liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

PEG10

Research Areas

Epigenetics and Nuclear Signaling;Cancer;Stem cells