PEA-15(Phospho Ser116) Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a death effector domain-containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.

Reactivity

Human, Mouse, Rat, Monkey

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human PEA-15 around the phosphorylation site of Ser116. AA range:81-130

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

15040

synonyms

Astrocytic phosphoprotein PEA-15; PEA15; Astrocytic phosphoprotein PEA-15; 15 kDa phosphoprotein enriched in astrocytes; Phosphoprotein enriched in diabetes; PED