PDZ-RhoGEF Polyclonal Antibody

Ab type

Primary antibody

Background

Periphilin 1 encoded by PPHLN1 is one of the several proteins that become sequentially incorporated into the cornified cell envelope during the terminal differentiation of keratinocyte at the outer layers of epidermis. Periphilin 1 interacts with periplakin, which is known as a precursor of the cornified cell envelope. The cellular localization pattern and insolubility of periphilin 1 suggest that it may play a role in epithelial differentiation and contribute to epidermal integrity and barrier formation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human ARHGEF11. AA range:198-247

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

167704

synonyms

ARHGEF11; KIAA0380; Rho guanine nucleotide exchange factor 11; PDZ-RhoGEF