Pdxp Antibody

Size

100ug

Clone Number

Aliases

Pdxp antibody; Cin antibody; Plp antibody; Plpp antibody; Pyridoxal phosphate phosphatase antibody; PLP phosphatase antibody; EC 3.1.3.3 antibody; EC 3.1.3.74 antibody; Chronophin antibody

Immunogen Species

Mus musculus (Mouse)

UniProt ID

P60487

Immunogen

Recombinant Mouse Pyridoxal phosphate phosphatase protein (1-292AA)

Raised in

Rabbit

Species Reactivity

Mouse, Rat

Tested Applications

ELISA, WB; Recommended dilution: WB:1:500-1:5000

Background

Protein serine phosphatase that dephosphorylates \\\'Ser-3\\\' in cofilin and probably also dephosphorylates phospho-serine residues in DSTN. Regulates cofilin-dependent actin cytoskeleton reorganization. Required for normal progress through mitosis and normal cytokinesis (By similarity). Does not dephosphorylate phospho-threonines in LIMK1. Does not dephosphorylate peptides containing phospho-tyrosine. Pyridoxal phosphate phosphatase. Has some activity towards pyridoxal 5\\\'-phosphate (PLP), pyridoxine 5\\\'-phosphate (PMP) and pyridoxine 5\\\'-phosphate (PNP), with a highest activity with PLP followed by PNP.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

Pdxp

Research Areas

Others