Pdk3 Antibody

Size

100ug

Clone Number

Aliases

Pdk3 antibody; [Pyruvate dehydrogenase antibody; acetyl-transferring)] kinase isozyme 3 antibody; mitochondrial antibody; EC 2.7.11.2 antibody; Pyruvate dehydrogenase kinase isoform 3 antibody

Immunogen Species

Mus musculus (Mouse)

UniProt ID

Q922H2

Immunogen

Recombinant Mouse [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial protein (131-362AA)

Raised in

Rabbit

Species Reactivity

Mouse, Human, Rat

Tested Applications

ELISA, WB; Recommended dilution: WB:1:500-1:5000

Background

Inhibits pyruvate dehydrogenase activity by phosphorylation of the E1 subunit PDHA1, and thereby regulates glucose metabolism and aerobic respiration. Can also phosphorylate PDHA2. Decreases glucose utilization and increases fat metabolism in response to prolonged fasting, and as adaptation to a high-fat diet. Plays a role in glucose homeostasis and in maintaining normal blood glucose levels in function of nutrient levels and under starvation. Plays a role in the generation of reactive oxygen species (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

Pdk3

Research Areas

Metabolism; Signal transduction