PDK1 Polyclonal Antibody

Ab type

Primary antibody

Background

Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for PDK1.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human PDK1. AA range:210-259

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

49244

synonyms

PDPK1; PDK1; 3-phosphoinositide-dependent protein kinase 1; hPDK1