PDHK1(Phospho Tyr243) Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human PDHK1 (Phospho Tyr243)

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

47960

synonyms

PDHK1 ;Phospho Tyr243; [Pyruvate dehydrogenase [lipoamide; ; kinase isozyme 1; mitochondrial; EC 2.7.11.2; Pyruvate dehydrogenase kinase isoform 1