Pdgfd Antibody

Size

100ug

Clone Number

Aliases

Pdgfd antibody; Scdgfb antibody; Platelet-derived growth factor D antibody; PDGF-D antibody; Spinal cord-derived growth factor B antibody; SCDGF-B) [Cleaved into: Platelet-derived growth factor D antibody; latent form antibody; PDGFD latent form); Platelet-derived growth factor D antibody; receptor-binding form antibody; PDGFD receptor-binding form)] antibody

Immunogen Species

Mus musculus (Mouse)

UniProt ID

Q925I7

Immunogen

Recombinant Mouse Platelet-derived growth factor D protein (24-370AA)

Raised in

Rabbit

Species Reactivity

Mouse, Human

Tested Applications

ELISA, WB, IF; Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200

Background

Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing (By similarity). Has oncogenic potential and can induce tumor formation. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

Pdgfd

Research Areas

Neuroscience; Cancer; Cardiovascular; Signal transduction