Pdcd-1 Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice| expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human Pdcd-1

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

31680

synonyms

Pdcd-1; Programmed cell death protein 1; Protein PD-1; hPD-1; CD antigen CD279