PCMT1 Antibody

Size

100ug

Clone Number

Aliases

PCMT1 antibody; Protein-L-isoaspartate(D-aspartate) O-methyltransferase antibody; PIMT antibody; EC 2.1.1.77 antibody; L-isoaspartyl protein carboxyl methyltransferase antibody; Protein L-isoaspartyl/D-aspartyl methyltransferase antibody; Protein-beta-aspartate methyltransferase antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P22061

Immunogen

Recombinant Human Protein-L-isoaspartate(D-aspartate) O-methyltransferase protein (117-228AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200

Background

Catalyzes the methyl esterification of L-isoaspartyl and D-aspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. Acts on EIF4EBP2, microtubule-associated protein 2, calreticulin, clathrin light chains a and b, Ubiquitin carboxyl-terminal hydrolase isozyme L1, phosphatidylethanolamine-binding protein 1, stathmin, beta-synuclein and alpha-synuclein.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

PCMT1

Research Areas

Cell biology