PCBP2 Antibody

Size

100ug

Clone Number

Aliases

Alpha CP2 antibody; Alpha-CP2 antibody; alphaCP-2 antibody; Cbp antibody; CTBP antibody; Heterogeneous nuclear ribonucleoprotein E2 antibody; Heterogenous nuclear ribonucleoprotein E2 antibody; hnRNP E2 antibody; hnRNP-E2 antibody; HNRNPE2 antibody; Hnrnpx antibody; HNRPE2 antibody; Hnrpx antibody; MGC110998 antibody; PCBP2 antibody; PCBP2_HUMAN antibody; poly(rC) binding protein 2 antibody; Poly(rC)-binding protein 2 antibody; Putative heterogeneous nuclear ribonucleoprotein X antibody; rCbinding protein 2 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q15366

Immunogen

Recombinant Human Poly(rC)-binding protein 2 protein (171-293AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500

Background

Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Binds also poly(rU). Negatively regulates cellular antiviral responses mediated by MAVS signaling (PubMed:19881509). It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitination and degradation (PubMed:19881509).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

PCBP2

Research Areas

Epigenetics and Nuclear Signaling; Microbiology