PBR Polyclonal Antibody

Ab type

Primary antibody

Background

Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by TSPO (translocator protein) interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from PBR . at AA range: 90-170

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

18779

synonyms

TSPO; BZRP; MBR; Translocator protein; Mitochondrial benzodiazepine receptor; PKBS; Peripheral-type benzodiazepine receptor; PBR