Pax-2 Polyclonal Antibody

Ab type

Primary antibody

Background

PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor suppressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of PAX2 results in multiple transcript variants.

Reactivity

Human;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human Pax-2. AA range:144-193

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

44734

synonyms

PAX2; Paired box protein Pax-2