Pax-1 Polyclonal Antibody

Ab type

Primary antibody

Background

PAX1 is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. PAX1 plays a role in pattern formation during embryogenesis and may be essential for development of the vertebral column. PAX1 is silenced by methylation in ovarian and cervical cancers and may be a tumor suppressor gene. Mutations in this gene are also associated with vertebral malformations.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human Pax-1. AA range:318-367

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

46295

synonyms

PAX1; HUP48; Paired box protein Pax-1; HuP48