PARVA Antibody

Size

100ug

Clone Number

Aliases

Actopaxin antibody; Alpha parvin antibody; Alpha-parvin antibody; Calponin like integrin linked kinase binding protein antibody; Calponin-like integrin-linked kinase-binding protein antibody; CH ILKBP antibody; CH-ILKBP antibody; FLJ10793 antibody; FLJ12254 antibody; Matrix remodelling associated 2 antibody; Matrix remodelling associated protein 2 antibody; Matrix-remodeling-associated protein 2 antibody; MXRA 2 antibody; MXRA2 antibody; PARV A antibody; Parva antibody; PARVA_HUMAN antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9NVD7

Immunogen

Recombinant Human Alpha-parvin protein (2-94AA)

Raised in

Rabbit

Species Reactivity

Human, Rat

Tested Applications

ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200

Background

Plays a role in sarcomere organization and in smooth muscle cell contraction. Required for normal development of the embryonic cardiovascular system, and for normal septation of the heart outflow tract. Plays a role in sprouting angiogenesis and is required for normal adhesion of vascular smooth muscle cells to endothelial cells during blood vessel development (By similarity). Plays a role in the reorganization of the actin cytoskeleton, formation of lamellipodia and ciliogenesis. Plays a role in the establishement of cell polarity, cell adhesion, cell spreading, and directed cell migration.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

PARVA

Research Areas

Signal transduction