PARL Antibody

Size

100ul

Clone Number

Aliases

Mitochondrial intramembrane cleaving protease PARL antibody; Mitochondrial intramembrane-cleaving protease PARL antibody; P-beta antibody; parl antibody; PARL_HUMAN antibody; Pbeta antibody; presenilin associated rhomboid-like antibody; Presenilins associated rhomboid-like protein antibody; PRO2207 antibody; PSARL antibody; PSARL1 antibody; PSENIP2 antibody; RHBDS1 antibody; Rhomboid 7 homolog 1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9H300

Immunogen

Recombinant Human Presenilins-associated rhomboid-like protein, mitochondrial protein (1-170AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of OPA1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apoptoptic signals (By similarity). Promotes changes in mitochondria morphology regulated by phosphorylation of P-beta domain.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

PARL

Research Areas

Neuroscience; Cancer; Cell biology; Metabolism